I'm odd man out. I found General Science NB to be.. restricting.
While it is prescheduled I didn't need that because I had a schedule I was happy with. I was frustrated that they put a lot of emphasis on vocabulary but had no place for that to be recorded. They had the kids record lots of the historical information shared & less of the scientific information. So for instance when talking about the Father Of Atoms, my child had to record that man's name, but had no place to record information about Atoms which he found far more fascinating then he did the man dubbed as the finder/discoverer/etc.
I also found it a little scattered. So the historical information per lesson is in the front. While flipping through I found random spots in the back for summaries which were literally fill int he blanks. I didn't use those because when my child summarised the reading for the day to me he was nearly word for word with what was there. He rocks at narrations.
The experiment stuff is in another location so it's not broken down by lesson as the Elementary versions are. So there's an entire section devoted to the experiments, which is fine, but it felt disjointed in the fact that each experiment was based on your readings so it made more sense to put it with those notes to help you keep track. Granted, a proper science notebook would be broken down a little differently with "lab reports", "Vocabulary", etc.
Anyway, for us it wasn't a hit, but then the only NB we've been SUPER happy with was the one that went alongside Anatomy Elementary. The rest were not bad, but limiting.